Category Archives: Funding

PCORI Funding Initiative: Symptom Management for Patients with Advanced Illness PFA for Cycle 2 2018.  

The Patient-Centered Outcomes Research Institute (PCORI) will be releasing the Symptom Management for Patients with Advanced Illness PFA for Cycle 2 2018.   

The goal of this funding initiative is to support patient- and caregiver-centered, comparative clinical effectiveness research to generate important findings that will aid decision making about symptom management in advanced illness. PCORI seeks to fund multiple high quality clinical studies that compare the effectiveness of evidence-based treatments for relief of common symptoms experienced by patients with serious, advanced illness. 

The mission of the PCORI is to improve the quality and relevance of evidence available to help patients, caregivers, clinicians, employers, insurers, and policy makers make informed health decisions. We invite you to review this funding announcement on our website and share this information with others who may be interested. 

The full funding announcement will be released on June 1, 2018. While this funding announcement was originally released in Cycle 2 2017, PCORI has made some changes to this version. We invite you to register for the Town Hall on June 19, 2018. 

If you have any questions, please contact [email protected].  

2018 Lasker Clinical Research Scholars Program

The National Institutes of Health, in partnership with the Lasker Foundation, is pleased to announce the 2018 Lasker Clinical Research Scholars Program. This is an opportunity for 8 to 10 years of funding for clinical researchers. This unique program provides Scholars with 5 to 7 years of support as an independent principal investigator in the NIH Intramural Research Program, followed by three years of continued financial support, either at the NIH or at an outside medical center/research institution.

Qualifications/eligibility:
Candidates must have a clinical doctoral degree (MD, MD/PhD, DO, DDS, DMD, RN/PhD or equivalent) and a professional license to practice in the United States. The program is intended for investigators at the early stages of their independent careers, and at the time of application, candidates must be no more than 10 years from completion of their core residency training. Candidates generally will have completed or will be completing a post-residency clinical fellowship and will have demonstrated significant patient-oriented research experience to qualify for a tenure-track level appointment.

Application deadline: August 31, 2018

For more information, please reference the documents attached here, or visit: https://www.nih.gov/research-training/lasker-clinical-research-scholars

Pragmatic Trials for Dementia Care in Long-term Services and Support Settings R61/R33

Funding Opportunity Number: PAR-18-585
CFDA Number: 93.866

National Institute on Aging (NIA) invites applications for pragmatic trials for dementia care in Long-term Services and Support (LTSS) settings which will: (1) be designed to address practical comparative questions faced by Alzheimer’s disease (AD) and AD-related dementia (ADRD) patients, clinicians and caregivers (both paid and unpaid); (2) include broad and diverse populations; and (3) be conducted in real-world settings. These trials are intended to produce results that can be directly adopted by healthcare providers, patients or caregivers for rapid translation.

Deadline Dates: Applications may be submitted on or after February 23, 2018. The deadline for receipt of optional letters of intent is 30 days prior to the application due date. The deadlines for receipt of full applications are: March 27, 2018; February 20, 2019; and February 20, 2020, by 5:00 PM local time of applicant organization. This FOA will expire on February 21, 2020.

For more details, visit: https://grants.nih.gov/grants/guide/pa-files/PAR-18-585.html

EOL and PC Health Literacy R01/R21: Improving Outcomes in Serious, Advanced Illness

Types of studies may include innovative methods or approaches such as qualitative, mixed methods, observational, quasi-experimental, and experimental with focus on individual- and family-centered outcomes. It is strongly encouraged that the investigative teams be interdisciplinary and include nurse scientists and early stage investigators. Investigators are also encouraged to consider using existing palliative care research networks, such as the Palliative Care Research Cooperative Group, to carry out small, multi-site trials when appropriate.

For more information, visit:

https://grants.nih.gov/grants/guide/pa-files/PA-18-498.html

Changing policies impact NIH-funded studies involving human subjects

Message to NIH grant applicants/awardees, contractors, researchers and research administrators:

If you are conducting NIH-funded research that involves human subjects, or are considering applying to NIH for support of such research, we want to call your attention to important changes that may affect how you:

  • select the right NIH funding opportunity announcement
  • write the research strategy and human subjects sections of your application
  • comply with appropriate policies and regulations

First, familiarize yourself with the new PHS Human Subject and Clinical Trial Information form (for application due dates of January 25, 2018).  Learn about the new form here.

Second, review  the updated NIH definition of a clinical trialVisit the NIH webpage on the definition that includes case studies, FAQs and other resources that can help. Still unsure?  Contact your NIH program official or the scientific point of contact listed on the funding opportunity announcement to which you are applying.

Third, familiarize yourself with NIH policy changes related to enhancing stewardship of clinical trials.

Visit the new Clinical Trial Requirements for NIH Grantees and Contractors web page to bring together all the information you need to know.  Please review this information carefully.  Your attention to detail will be critical to ensuring successful funding of your clinical trial awards. 

Funding Opportunity Announcement (FOA) Webinar

National Cancer Institute: Healthcare Delivery Research Program

Funding Opportunity Announcement (FOA) Webinar:  

Intervening with Cancer Caregivers to Improve Patient Health Outcomes and Optimize Health Care Utilization

When: August 17, 2017 from 2:00 PM – 3:00 PM ET

Where: via WebEx (Register Here)

 Presenters: Dr. Erin Kent and Dr. Michelle Mollica

 

Summary: This webinar will provide an overview of the R01/R21 Funding Opportunity Announcement (FOA), Intervening with Cancer Caregivers to Improve Patient Health Outcomes and Optimize Health Care Utilization: Funding Opportunity (PAR-16-317/PAR-17-318).  This FOA invites applications for intervention research designed to support caregivers of adult cancer patients. Interventions are intended to provide caregivers with care training, promote coping skills, and ultimately help them manage care. Outcomes of such interventions are expected to (1) optimize patient health care utilization, (2) improve caregiver well-being, and (3) improve patient physical health and psychosocial outcomes.  The next receipt dates for all types of applications (new and resubmissions) are October 10, 2017; April 11, 2018; October 10, 2018; and April 11, 2019.  For more information about cancer caregiving research at NCI, please see our website.

PCRC Data Repository Expansion Grant Awards

The PCRC is pleased to announce two sets of awards.

Congratulations to the award winners of the PCRC grants to support the secondary analysis of existing data in the PCRC Data Repository.  The award winners are:

  • Kathleen M. Akgün, MD, MS, Yale School of Medicine, “Polypharmacy, statin use and 6-month dyspnea trajectories among older adults with serious, life-limiting diseases”
  • Angela Ghesquiere, PhD, MSW, Hunter College, City University of New York, “Exploring Psychological Symptoms as Moderators of Treatment Outcomes in the REST Study”
  • Yael Schenker, MD, MAS, University of Pittsburgh Montefiore Hospital, “Associations between polypharmacy, symptom burden, and quality of life in patients with advanced, life-limiting illness”

The PCRC is thrilled to support these investigators and learn of the findings from their secondary data analyses!

The PCRC also is expanding the PCRC Data Repository to include data from completed end-of-life and palliative care (EOLPC) studies that may have been conducted outside of the PCRC and without PCRC support. In late April, the PCRC published a funding announcement to support the data repository expansion initiative, and we are excited to announce that the PCRC Data Repository will be expanded to include study data from 11 EOLPC research projects! Once incorporated into the PCRC Data Repository, these data will be available to investigators for secondary data analyses. Please see the table below with information about the studies.

Datasets to be included in PCRC Data Repository: Award Winners
Principle Investigator Institution Study Title 
Benzi Kluger, MD, MS University of Colorado Does Outpatient Palliative Care Improve Patient-Centered Outcomes in Parkinson’s Disease
Margaret L. Campbell PhD, RN, FPCN Wayne State University Is death rattle a phenomenon that requires medical treatment?
Margaret L. Campbell PhD, RN, FPCN Wayne State University Rater intensity psychometrics for the Respiratory Distress Observation Scale
Margaret L. Campbell PhD, RN, FPCN Wayne State University Intensity cutpoints substantiation of the Respiratory Distress Observation Scale
Matthew R Baldwin, MD, MS Columbia University Frailty and Outcomes in Critical Illness Survivors-I (FOCIS-I)
Katherine R. Courtright, MD, MS University of Pennsylvania Choice Sets for Advance Directives
Stacy Fischer, MD University of Colorado Apoyo con Carino: (Support Through Caring) Improving Palliative Care Outcomes for Latinos with Advanced Cancer
Amber E. Barnato, MD, MPH, MS University of Pittsburgh Consumer Engagement
Amber E. Barnato, MD, MPH, MS University of Pittsburgh Organizational and Provider Norms of Life-sustaining Treatment Decision Making
Amber E. Barnato, MD, MPH, MS University of Pittsburgh Surrogate’s Heightened Emotions and Life support Decisions (SHEALD)
David Bekelman, MD, MPH VA Eastern Colorado Health Care System Collaborative Care to Alleviate Symptoms and Adjust to Illness in Heart Failure: Randomized Clinical Trial

The investigator and his/her analyst have been invited to attend a half-day workshop in Denver on Tuesday, June 13, 2017 to learn best practices for reproducible research and how to prepare data for inclusion in the repository. The training will be led by the current and former PCRC Data Informatics and Statistics Core (DISC) Directors, Dr. Katie Colborn and Dr. Diane Fairclough, respectively.  This workshop will be recorded (using Zoom), which can then be made available to other investigators wishing to utilize this valuable resource.  Stay tuned!

We encourage you to consider including any study data you may have for which you think additional secondary data analysis could be conducted and support those who need access to these datasets for preliminary data and/or grant proposal preparation.  Thank you in advance for considering adding your work to and conducting secondary analyses using the PCRC’s growing data repository!

For information about how to request data from the PCRC Data Repository or add study data to the PCRC Data Repository, please click here

Upcoming FOA from PCORI

A new, upcoming funding opportunity from the Patient-Centered Outcomes Research Institute (PCORI), entitled, “Symptom Management for Patients with Advanced Illness” will be announced on June 23, 2017.  This advanced notice, which can also be found on the PCORI website, is being provided to allow potential applicants additional time to identify collaborators, obtain stakeholder input on the research question, and develop responsive, high-quality proposals.

Please email [email protected] with any questions related to this funding announcement and please see below for further details about this upcoming funding opportunity.