The PCRC was established in large part to help overcome the many challenges of conducting multi-site research. If you are interested in conducting multi-site research, the PCRC supports investigators by:
- Taking clinical research ideas from concept to study design through consultation with expert PCEOL research leaders through our PCRC Cores and Centers.
- Providing replicable infrastructure, processes, tools, and methods, including evaluative metrics, to support efficient and effective cooperative group function.
- Developing a comprehensive protocol and study-specific materials including data collection tool (DCT), case report forms (CRFs) and a site training manual.
- Developing a study calendar to clarify metrics and meet deadlines.
- Training site-based study personnel, creating a study database with web-based electronic data capture, and facilitating Institutional Review Board (IRB) approval at each site.
- Implementing study-specific Standard Operating Procedures (SOPs).
- Assisting with enrollment initiation, supporting accrual throughout the study, and ensuring high quality data collection.
- Developing and supporting Data Safety and Monitoring Board (DSMB ) activities.
- Establishing an Event Classification Committee (ECC) to confirm endpoint assessments and provide a quality assurance mechanism.
- Providing regular tracking and monitoring of study performance metrics in order to refine study processes and optimize efficiency.
- Refining processes based on lessons learned across studies and sites.
- Supporting publications of findings in accordance with the PCRC Authorship Protocol to advance the quality, productivity and impact of PCEOL research.